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已发表论文

大鼠的视神经受损后骨髓间充质干细胞的治疗作用

 

Authors Tan HB, Kang X, Lu SH, Liu L

Published Date February 2015 Volume 2015:10 Pages 487—490

DOI http://dx.doi.org/10.2147/CIA.S75319

Received 2 October 2014, Accepted 9 November 2014, Published 16 February 2015

Abstract: Optic nerve trauma is a common occurrence that results in irreversible blindness. Currently, no effective strategies are known to prevent optic nerve degeneration. We assessed the therapeutic effects of bone marrow mesenchymal stem cells (BMSCs) after optic nerve crush in the adult rat. Our results showed that BMSCs significantly promoted the regeneration of injured axons compared with phosphate buffered saline alone. Therefore, BMSC transplantation may be effective for the treatment of central nervous system disorders.
Keywords: bone marrow mesenchymal stem cell, axonal regeneration, rat optic nerve crush, nervous system disorders


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