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已发表论文

熊去氧胆酸与布地奈德联合治疗原发性胆汁性肝硬化 (PBC)-自身免疫性肝炎 (AIH) 重叠综合征 : 综合分析

 

Authors Zhang H, Yang J, Zhu R, Zheng Y, Zhou Y, Dai W, Wang F, Chen K, Li J, Wang C, Li S, Liu T, Abudumijiti H, Zhou Z, Wang J, Lu W, Wang J, Xia Y, Zhou Y, Lu J, Guo C

Published Date January 2015 Volume 2015:9 Pages 567—574

DOI http://dx.doi.org/10.2147/DDDT.S74515

Received 18 September 2014, Accepted 1 November 2014, Published 17 January 2015

Abstract: In this study, a meta-analysis of randomized controlled trials comparing ursodeoxycholic acid (UDCA) monotherapy with combination therapies utilizing UDCA and budesonide was performed. We found that combination therapy with UDCA and budesonide was more effective than UDCA monotherapy for primary biliary cirrhosis–autoimmune hepatitis overlap syndrome. Moreover, compared to prednisone, budesonide has fewer side effects.
Keywords: meta-analysis, UDCA, budesonide, combination therapy, PBC–AIH overlap syndrome


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